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SSHD molecules



The COQ4 gene plays an important role in production of the vital energy producing enzyme CoenzymeQ10. Enough CoenzymeQ10 is necessary to supply the energy needed for all the body's organs and cells to work at their optimum capacity, especially skeletal muscle, heart muscle, the liver and the immune system.

Without CoenzymeQ10, no energy is produced, and cells and organs die. CoenzymeQ10 is considered to have important anti-aging properties, therefore everyone would benefit by taking this product on a permanent basis as they age. The SSHD-CQ4 molecule optimises the function of gene COQ4.

What does COQ4 do?

The gene COQ4 encodes a protein that is responsible for organising a multienzyme complex for the synthesis of CoenzymeQ10. It has been shown to be an essential requirement for the production of biological energy in all forms of life.

In 2008, Casarin and co-workers first discovered the same vital energy producing gene in humans [1]. Since then, other scientists have demonstrated that reduced expression of the COQ4 gene leads to partial CoenzymeQ10 deficiency, and subsequently, increased susceptibility to development of many disorders [2].

CoenzymeQ10 is essential for production of ATP in the cell's mitochondria as part of the Kreb’s cycle. ATP is the body’s vital energy source, the body's "vital force" according to the homeopath S. Rashid [3]. It is the body’s source of power, just like a battery. Therefore, if insufficient CoenzymeQ10 is available, the biological battery loses power and cells and organs die.

Roffe and colleagues discovered yet further benefits of CoenzymeQ10 in that it can reduce unwanted side-effects in cancer patients receiving chemotherapy [4].

Unfortunately, statin drugs impair CoQ10 synthesis. They do this by blocking the conversion of the CoenzymeQ10 precursor hydroxymethylglutarate to cholesterol and then subsequently to CoenzymeQ10 [5]. Therefore, it would be of great benefit to optimise the function of the COQ4, to benefit to all those who are on long term statin therapy.

Finally, in view of the fact that CoenzymeQ10 is so important in recharging all the body’s energy batteries, it is not surprising that Hoppe and colleagues referred to it well over a decade ago as an "energizer" [6].


  1. Casarin et al, Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis. Biochem. Biophys. Res.Commun. 372:35, 2008.
  2. Salviati et al., Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency. J. Med. Genet. 49:187, 2012. doi: 10.1136/jmedgenet-2011-100394.
  3. http://hpathy.com/homeopathy-papers/vital-force-generation-and-utilisation/.
  4. Roffe et al.,Efficacy of coenzyme Q10 for improved tolerability of cancer treatments: a systematic review. J Clin Oncol. 22:4418, 2004.
  5. Levy and Kohlhaas., Considerations for supplementing with coenzyme Q10 during statin therapy. Ann Pharmacother. 40:290, 2006.
  6. Hoppe et al., Coenzyme Q10, a cutaneous antioxidant and energizer. Biofactors. 9:371, 1999.

Want to know more?

For more information about this SSHD molecule, contact your healthcare practitioner or arrange an appointment using our clinic.

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